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Under the current regional rule, clenbuterol may not be administered to a horse within 14 days of a race, and the concentration of the drug in a post-race blood sample may not exceed 140 picograms/ml. Abstract Clenbuterol is a beta (2)-agonist and potent selective bronchodilator that is used to treat bronchospasm in the horse. The drug is normally administered to horses orally as a syrup formulation. Bruker Chemical and Applied Markets (CAM), Fremont, California, US: A new article has been made available by Bruker detailing the use of the EVOQTM liquid chromatography triple quadrupole mass spectrometer (LC-TQ) for the analysis of the prohibited drug clenbuterol in equine plasma. Metal & Mineral Panel (ICP/MS) Measurement of metals and minerals by inductively-coupled plasma/mass spectrometry. Targets include manganese, cobalt, copper, iron, molybdenum, selenium, zinc, arsenic, cadmium, lead, and thallium. 75 sample preparation fee will be added to tissue and feed specimens. Background Clenbuterol is a β2-adrenoceptor agonist. It is assigned a 3/B in the ARCI’s Uniform Classification of Foreign Substances. For Quarter Horse racing it is designated as a prohibited substance and assigned a Class A penalty. Testing of nearly 100 Thoroughbreds previously raced by trainers indicted in March on performance-enhancing drug charges indicated that 77% showed the presence of clenbuterol, according to Dr
Oral bioavailability of clenbuterol is 80–90% and albuterol is 40–50%. Clenbuterol crosses the blood brain barrier better than less lipid soluble b 2-ago-nists such as albuterol. The higher lipid solubility also results in accumulation of clenbuterol in tissues with a high lipid content such as fat depots and liver. Under the current regional rule, clenbuterol may not be administered to a horse within 14 days of a race, and the concentration of the drug in a post-race blood sample may not exceed 140 picograms/ml. Frequently Used Equine Tests. Complete Blood Count (CBC) and Chemistry/Biochemistry Testing. Corynebacterium pseudotuberculosis (pigeon fever) – CAHFS, UCD veterinary hospital Clinical Laboratory. Learn more about pigeon fever in horses here. Equine Blood Type and Antibody Screen (including neonatal isoerythrolysis (NI)). Bruker Chemical and Applied Markets (CAM), Fremont, California, US: A new article has been made available by Bruker detailing the use of the EVOQTM liquid chromatography triple quadrupole mass spectrometer (LC-TQ) for the analysis of the prohibited drug clenbuterol in equine plasma. Clenbuterol, along with good stable management that reduces the horse's exposure to dust and to high ammonia concentrations from urine in poorly ventilated stalls, is used to manage chronic obstructive pulmonary disease. Horse owners and handlers sometimes use clenbuterol as a performance-enhancing drug in racehorses. Five horses received oral clenbuterol (0. ) for 10 days, and urine concentrations of clenbuterol were determined by an enhanced enzyme-linked immunoabsorbent assay (ELISA) test and gas chromatography/mass spectrometric (GC/MS) analysis by two different methods for 30 days after administration Where to buy clenbuterol for horses
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